Adipose Tissue in Health and Disease
Todd Leff, James G. Granneman
John Wiley & Sons, Mar 19, 2010 - Science - 530 pages
This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic.
Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue.
The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.
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Part Two Metabolic Functions of Adipose Tissue
Part Three Endocrine Functions of Adipose Tissue
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abdominal activity acyl-CoA adipocyte differentiation adipocytes adipogenesis adipogenic adipokines adiponectin adipose organ AQP7 associated ATGL binding Biochem Biol Biophys body fat brown adipocytes cancer Chem circulating Clin cytokines decreased disease effects Endocrinol energy fat depots fatty acid ﬁrst function gene expression genetic glucose glycerol growth hepatic hormone human adipose tissue human fat cells hypertension identiﬁed increased induced infection inﬂammation inﬂammatory inﬂuence inhibition insulin resistance insulin sensitivity knockout leptin levels lipase lipid droplets lipodystrophy lipolysis lipolytic lipoprotein lipoprotein lipase liver macrophages mechanisms mediated membrane Metab metabolic syndrome mice molecular mRNA mutations Natl omental oxidative pathways patients peroxisome proliferator-activated peroxisome proliferator-activated receptor phenotype phosphorylation Physiol plasma PLIN PPAR-y preadipocytes proﬁle promoter rats receptor reduced regulation resistin role secretion serum signaling signiﬁcant skeletal muscle speciﬁc stimulation studies subcutaneous subcutaneous adipose tissue transcription factors transgenic triacylglycerol triglyceride tumor type 2 diabetes uptake visceral fat vitro vivo