Adrenomedullin in Cardiovascular Disease

Front Cover
Toshio Nishikimi
Springer Science & Business Media, Mar 30, 2006 - Medical - 219 pages
0 Reviews

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis.

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Adrenomedullin Gene
56
Biological Action of Adrenomedullin
83
Circulating Adrenomedullin
105
Role of Adrenomedullin in
131
Adrenomedullin as an Adipokine
155
Adrenomedullin Knockout Mouse and
167
175
174
Therapeutic Application of
187
Therapeutic Potentials of
199
Index
215
Copyright

Other editions - View all

Common terms and phrases

About the author (2006)

Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

Bibliographic information