Advanced Therapy for Hepatitis C

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Geoffrey W. McCaughan, John McHutchison, Jean-Michel Pawlotsky
John Wiley & Sons, Oct 5, 2011 - Medical - 232 pages
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Hepatologists, both researchers and front-line clinicians, now have a comprehensive guide to the treatment of patients with the HCV virus. This book focuses mainly on the efficacy and clinical use of antiviral therapies, including the use of antivirals post liver transplantation and in the presence of the HIV virus. It also explores the foundations for understanding antiviral therapies in HCV, such as the complex pharmacology and mechanisms of antiviral drugs. A 'late-breaking information' chapter contains the most recent trial results on the latest antiviral drugs.

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Hepatitis C Virus Genotypes
GenotypeSpecific Effects of HCV Proteins
Mechanisms of Action of Antiviral Drugs
Pharmacology and Mechanisms of Action
Management Strategiesfor CHC in the Setting of
Pharmacology and Mechanisms of Action
Measuring Antiviral Responses
Hepatitis C Genotype 4 Therapy
The Efficacy of Different Pegylated Interferon
Antivirals in Acute Hepatitis C
Duration of Therapy
Treatment of Recurrent Hepatitis C
Antiviral Treatment in Chronic Hepatitis
Cytopenias How they Limit Therapy
The Problem of Insulin Resistance

Genotype 1 Standard Treatment
Individually Tailored Treatment
Genotype 1 Relapsers and Non
Standard Therapyfor Genotypes
Altered Dosage or Durations of Current
Genotypes 2 and 3 Relapse and Non
Management of Relapse or Nonresponse to Antiviral
HIV and Hepatitis C Coinfection
HCV and Racial Differences Introduction
HCV and the Pediatric Population
New Horizons IL28 Directacting
Summary and Conclusions

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About the author (2011)

Professor Geoff McCaughan is Director of the AW Morrow Liver Centre and Physician in Charge at the Australian National Liver Transplant Unit.

John McHutchison is a professor of medicine at Duke University Medical Center, and since 2002, Director of the DCRI’s Gastroenterology and Hepatology Research division.

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