Advanced Diagnostic Methods in Pathology: Principles, Practice, and Protocols
This new text is devoted to the use of immunopathological, molecular biologic, flow cytometric and image analysis techniques in the diagnostic pathology laboratory. It is an extremely comprehensive and practical work which considers both diagnostic and prognostic applications. Divided into three sections that deal with theory, techniques, and organ system specific diagnostic problems.
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A N C E D DI AG N O S T C M ETH ODS 1 Timothy j OLeary
Oncogenes and Tumor Suppressor Genes Ronald M Przygodzki and Michael N Koss
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abnormalities activity adenocarcinoma adenomas allele amino acid amplification analysis antibody antigen apoptosis assay associated BCL2 binding Biol biopsy Cancer Genet Cytogenet Cancer Res cell carcinoma cell lung cell tumors chromosome clinical clonal collagen cyclin D1 Cytogenet deletions demonstrate detection diagnosis differentiation disease domain enzyme ERBB2 expression factor flow cytometry genomic histologic human hybridization identified immunoglobulin immunohistochemical immunohistochemistry Immunoreactivity infection keratin kinase lesions lung cancer lymphoma lysate malignant markers master mix MDM2 melanoma membrane methods molecular molecule monoclonal mRNA mutations Natl Acad Sci neoplasms non-small cell nucleic acid Oncogene Oncol overexpression pathway patients polymerase chain reaction polymorphism primers probe Proc Natl Acad prognostic prostate protein reagents rearrangement receptor region renal retinoblastoma sample sarcoma sequence signal small cell Southern blot specific specimens staining syndrome T-cell target telomerase thyroid tion transcription translocation tube tumor suppressor gene virus