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Mechanisms of Hydroxylations in Bile Acid Biosynthesis I B6RxHEM
The Biosynthesis of Bile Acids and its Control K A MITROPOULOS
Stable Isotopes MassSpectrometry and 13C NMR in Studies of Bile Acid Bio
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Acta administration amount animals bile acid concentration bile acid excretion bile acid metabolism bile acid output bile acid pool bile acid synthesis bile acids bile duct bile flow bile salt Biochem biosynthesis cheno chenodeoxycholic acid cholate cholestasis cholesterol cholesterol-7a-hydroxylase cholestyramine cholic acid chromatography cirrhosis clin co-lipase colon conventional rats cytochrome P-450 decreased deoxycholic acid diet dose effect enterohepatic circulation enzyme enzyme activity ethinyl-estradiol experiments extrahepatic fecal bile acids ﬁnd ﬁndings ﬁrst fraction gallbladder gallstones Gastroenterology germfree glucuronides hepatic HMG-CoA reductase HOFMANN hydroxylation ileal resection increase incubation inhibition injected intestinal isotope labelled lecithin lipid lithocholic acid liver liver microsomal measured microsomal molecules normal oxalate absorption perfusion phenobarbital phototherapy plasma protein radioactivity rat liver ratio saturation secretion serum bile acids signiﬁcant signiﬁcantly solubility speciﬁc activity steroids studies substrate sulfated sulphate taurine taurochenodeoxycholic acid taurocholic acid total bile acid treatment urine