Advances in Cholesterol Research

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CRC Press, Aug 9, 1990 - Medical - 423 pages
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Advances in Cholesterol Research presents a range of topics which, for the most part, have not been reviewed in recent years in books published on cholesterol. The subject area can be divided into two main sections. The intracellular and extracellular dynamics of cholesterol. The intracellular dynamics of cholesterol includes the intracellular distributions of cholesterol, cellular functions of the sterol, cholesterol metabolism in steroidogenic tissues, the cholestryl ester cycle, relation between cholesterol and dolichol biosynthesis, and the role of cholesterol in tumor cell proliferation. The section on extracellular dynamics of cholesterol includes the biogenesis of high density lipoprotein subclasses, structure-function relation in lecithin: cholesterol acyltransferase, and the role of cholesterol in atherosclerosis and in membrane fusion.
 

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Contents

Transmembrane Cholesterol Distribution
47
The Biosynthesis of Dolichol and Its Relation
89
Role of Cholesterol in Cellular Functions
111
Lipoprotein and Cholesterol Metabolism
133
Intracellular Cholesteryl Ester Hydrolysis
171
The Role of the Cholesterol Synthesis Pathway
201
Cholesterol Acyltransferase
271
Conversions in the Origins and Metabolism
315
Modulation of Membrane Fusion
367
Role of Cholesterol in Atherosclerosis
385
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