Advances in Clinical Chemistry, Volume 43
Elsevier, Dec 27, 2006 - Science - 304 pages
Volume 43 of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. In this volume, the biochemistry of bilirubin, the end-product of heme metabolism, is explored with respect to its potential beneficial role in preventing oxidative changes associated with a variety of pathological conditions, including atherosclerosis, cancer, and inflammatory, autoimmune and other degenerative diseases.
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Cyclooxygenase2 and Tumor Biology
Oligonucleotide Probes for RNATargeted Fluorescence In Situ Hybridization
Activin A in Brain Injury
Methods for Predicting Human Drug Metabolism
A Summary Analysis of Down Syndrome Markers in the Late First Trimester
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activin activity allele allograft angiogenesis anti‐inflammatory antioxidant apoptosis assay associated atherosclerosis aYnity bilirubin biliverdin binding Biochem Biophys breast cancer Cancer Res cardiovascular Case/control clearance Clin Pharmacol clinical colorectal colorectal cancer computational coronary correlation COX‐2 expression cyclooxygenase‐2 cytochrome P450 database detection disease diVerent diVerentiation Drug Metab Dispos drug metabolism Ekins endothelial cells enzymes estrogen estrogen metabolism eVects factors fluorescence function genetic heme oxygenase heme oxygenase‐1 hepatic hepatocytes hybridization hydroxylation increased induced inhibition inhibitors interactions liver lung markers maternal serum mediated metabolites methods microsomes models molecules mRNA Nucleic Acids Res OHE1 oligonucleotide oligonucleotide probes oxidative stress PAPP‐A pathway patients pharmacokinetics pharmacophore Physiol plasma polymorphism prediction pregnane X receptor Protects protein QSAR receptor risk role screening serum bilirubin concentrations standard deviation structure studies substrates syndrome pregnancies target tissue Toxicol trimester tumor unaVected variants vascular vitro vivo weeks