Advances in haemapheresis: Proceedings of the Third International Congress of the World Apheresis Association. April 9–12,1990, Amsterdam, The Netherlands

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Cees Smit Sibinga, L. Kater
Springer Science & Business Media, Jul 31, 1991 - Medical - 270 pages
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The first International Meeting on Apheresis was held in Dyon in 1984. At the congress it became clear that both the technical and therapeutic sides developed very rapidly and it appeared fruitful to bring together the investigators of the different countries working in the areas. At that time immunology had come to pervade many clinical specialities, and hemapheresis, especially plasmapheresis was considered a therapeutic tool in many immunological diseases which hitherto had proved to be fatal. New methods to identify certain antibodies and circulating immune complexes in the serum and the possibilities to remove them from the blood by several techniques (filtration, centrifugation, immunoabsorp tion) led to an almost uncontrolled use of plasma exchange in a variety of diseases. Since then the technical possibilities of this technique were further recognized, as was the impact of immunology on many diseases, and the possibilities to collect specific components for therapeutic pur poses. But also we became aware of the limited contributions of anec dotal data on successes or failures of apheresis as adjuvant treatment. Therefore international prospective studies were initiated to make critical assessment possible of apheresis in various diseases.
 

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Contents

Centrifugation versus filtration
1
The advantages of centrifugation in therapeutic plasmapheresis
5
High performance systems for membrane plasmapheresis
13
Two year clinical experience using a rotating filter for therapeutic plasma exchange
21
Donor plasmapheresis technology
29
Plasma exchange in peripheral neuropathy
40
Plasma exchange and GuillianBarre syndrome
51
Are immunoglobins superior to plasma exchange in the GuillainBarre syndrome?
59
Peripheral blood stem cell transplants in myeloma
133
High dose chemotherapy and blood stem cell autologou graft in multiple myeloma
139
A new perspective
145
A perspective for hematopoietic growth factors
153
Immunotherapy for hematological malignancies
159
The promise of T cell immunotherapy of cancer
165
A new approach to the management of Tcell mediated disorders
173
High levels of circulating hematopoietic progenitor cells after continuous infusion of high dose interleukin2 in cancer patients
189

Plasmapheresis in neurological disorder
69
The value of plasma exchange
79
Autologous transplantation of blood versus marrow derived hemopoietic stem cells
85
Granulocyte macrophage progenitor numbers in perpheral blood stem cell autotransplantation
91
Better or worse than circulating stem cells?
103
Purification and clinical results
113
Collection and transplantation of peripheral hemopoietic stem cells Results in 35 patients with hematological and nonhematological malignancies
119
Is leukocyte depletion important in the prevention of alloimmunization by random single donor platelet transfusion?
197
Effects on the immune system and on platelet function viability and alloimmunization
205
Elutriated single versus pooled donor platelets
229
Platelet concentrates from buffy coats
245
Selection of platelet apheresis donors for alloimmunized patients by ELISA platelet crossmatch versus HLAmatching
255
INDEX
263
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