Advances in Malignant Hematology

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Hussain I. Saba, Ghulam Mufti
John Wiley & Sons, Feb 23, 2011 - Medical - 440 pages
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This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publications. This book is written by experts from the American and European continent, sharing their current thoughts and knowledge on the pathobiology of malignant haematological diseases of the blood, as well as current treatment strategies and future developments in the area of these haematological diseases.
 

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Contents

Normal and Malignant Hematopoiesis
3
The Leukemia Genome
31
Myeloproliferative Neoplasms
49
Molecular Pathogenesis of BCRABL in Chronic Myeloid Leukemia
62
Standard Management of Patients with Chronic Myeloid Leukemia
71
The Molecular Biology of Acute Myeloid Leukemia
86
Acute Myeloid Leukemia
103
Acute Promyelocytic Leukemia
127
Chronic Lymphocytic Leukemia 211 Terry Hamblin and Angela Hamblin
228
Large Granular Lymphocyte Leukemia
244
Molecular Basis of Bcell Lymphomas
266
Peter McLaughlin
274
Hodgkin Lymphoma
296
Molecular Biology Diagnosis and Treatment
317
Waldenstroms Macroglobulinemia
342
Primary Systemic Amyloidosis AL
355

Evolving
143
A Review of Current Care
153
Supportive Care in Myelodysplastic Syndrome
172
Molecular Biology of Chronic Lymphoproliferative Disorders
193
Jorge Cortes St Vincents Comprehensive Cancer Center New York
211
Progress
369
Quality of Life after the Diagnosis of Hematological Malignancies
384
Index
399
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About the author (2011)

Hussain I. Saba, Department of Medicine, University of South Florida College of Medicine; James A. Haley Veterans Hospital; H. Lee Moffitt Cancer Center and Research Institute; , Tampa, FL, USA

Ghulam Mufti, Department of Haematological Medicine, Guy’s and St. Thomas’s School of Medicine, King’s College Hospital, London, UK

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