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POSSIBLE FUNCTIONS OF THE PEPTIDE ANTIBIOTICS TYROCIDINE AND GRA
A companion volume to this series entitled Current Developments in Yeast Research
THE ROLE OF SECONDARY METABOLISM IN Venicilliwn breviaompaatum
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ABSTRACT activity added addition agar amino acids amount antibiotic Bacillus Biochem biosynthesis biotin broth candicidin carbon cells cellulase Chem chemical chloramphenicol chromatography co-workers complex compounds concentration containing conversion culture decrease Demain derived described determined DISCUSSION effect enzyme experiments extract fermentation formation formed fraction fusion genetic glucose gramicidin grown growth immobilized incorporation increased incubation indicated inhibition intermediates INTRODUCTION involved isolated lysine Martin material mechanism medium metabolism metabolites method microbial Microbiol mixture mutants mycelium nitrogen observed obtained organism pathway penicillin phase phosphate plasmid possible precursor prepared present production properties protein protoplasts reaction REFERENCES regulation relatively reported repression respectively secondary showed shown similar solution specific spiramycin stimulation strains Streptomyces structure studies substrate sugar suggested synthesis synthetase Table temperature tion various yeast yield