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Brain Neurotransmitter Changes in Brains of Aged Rats
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3H]spiroperidol adenylate cyclase administration affinity age-related aged rats Agnoli agonist analysis animals apomorphine behavior binding sites biochemical blood flow Brain Res bromocriptine cerebral cerebral cortex cerebrovascular changes chronic clinical cognitive correlation cortex decrease DHA binding dihydroergocristine dihydroergotoxine disease dopamine receptors dopaminergic dopaminergic ergot derivatives dose double-blind edited effects elderly ergot alkaloids ergot drugs estrogen estrous cycle estrus evaluation female rats function geriatric hormone Hydergine hyperprolactinemia hypothalamus hypoxia impairment improvement increase inhibition injection lisuride male rats measured membrane metabolism mg/kg months neuroleptic neurological neurons neurotransmitter normal nucleus accumbens observed oxygen patients pergolide Pharmacol Pharmacology pineal gland pituitary placebo plasma prolactin prolactin levels rat brain Raven Press reduced response Sandoz SCAG scores SDAT senescent senile dementia serotonin significant spiroperidol stimulation striatal striatum subjects symptoms synaptosomes Table tardive dyskinesia therapy tion tissue treatment tryptophan vivo weeks York