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Animal Models for the Human Menopause
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acyclicity adrenal age-related aging rats androgens androstenedione aneuploidy associated Biol birth blood breast cancer cells changes chromosome circadian rhythm Clin clinical concentrations decreased disease disorders Effect of age endocrine Endocrinol Endocrinology endometrial cancer estradiol estrogen receptor estrogen therapy estrous factors Felicio female rats fertility Figure Finch follicles follicular frequency function Genet GnRH gonadotropin Gosden Gynecol Holinka hot flushes human hypothalamic increased infertility Judd LH secretion LH surges LHRH loss luteinizing hormone Medical menopause menstrual cycle Metab metabolism mice mouse mutation neuroendocrine Nieschlag normal nuclei Obstet older oocytes osteoporosis ovarian cancer ovariectomized ovary ovulation parental age paternal age paternal age effect perimenopausal physiologic pituitary plasma population postmenopausal postmenopausal women pregnancy progesterone progestin prolactin pulsatile rates reported Reprod response risk RNA polymerase rodents Roth samples senescent serum sexual activity significant Siiteri steroid stimulation studies syndrome testicular testosterone testosterone levels tissue uterine vaginal young