Airways and Vascular Remodelling in Asthma and Cardiovascular Disease: Implications for Therapeutic InterventionClive Page, Judith Black Vascular diseases and asthma are two common diseases associated with considerable morbidity and mortality. Both are chronic, each has an inflammatory component, both are accompanied by remodelling of hollow tubes and both are amenable to early intervention. This book compares and contrasts research progress made in each area, including our current understanding of the pathophysiology involved and the results of large-scale multicentre trials. |
Contents
Markers of Endothelial Cell | 21 |
Vascular Smooth Muscle in Culture and its Relevance to the Study | 27 |
vi | 34 |
Copyright | |
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Common terms and phrases
activity adhesion agonists airway narrowing airway responsiveness airway smooth muscle airway wall allergen Allergy Clin antigen antiplatelet antiproliferative aspirin asthma atherosclerosis basement membrane beclomethasone bFGF binding Biochem bronchoconstriction budesonide calcium channels Campbell carotid artery Castellot Cell Biol Cell Physiol cell proliferation cellular changes chronic clinical Clowes collagen contractile cromolyn culture denudation disease Edelman effects of heparin endothelial cells endothelium eosinophils epithelial epithelium extracellular matrix Gabbiani heparan sulphate heparin heparin inhibits heparin-like human hyperplasia Immunol inflammatory inhaled corticosteroids inhibitory intimal thickening Jeffery Karnovsky Kotlikoff Laitinen lamina layer lesion leucocytes Lindner lung macrophages mast cells mechanisms mediators mitogens modulation mRNA muscle shortening myocardial infarction myointimal thickening nedocromil nedocromil sodium normal patients PDGF phenotype platelets protamine protein proteoglycans Pukac pulmonary receptor reduced Reidy REMODELLING resistance Respir SMC proliferation smooth muscle cells studies thickness tissue treatment trial vascular smooth muscle vessel wall vitro vivo voltage-dependent calcium channels VSMCs Woolcock