Alcohol and Cancer
Ronald R. Watson
CRC Press, May 22, 1992 - Medical - 288 pages
Alcohol clearly plays key roles in the promotion of cancers initiated by carcinogens. Thus, it is a major cause or significant contributing factor to many cancers. Ethanol affects the metabolism of anticancer drugs. It significantly contributes to viral hepatitis and liver cancer. In addition it modulates colorectal carcinogenesis, procarcinogen activation and risk of oral cancers. The mechanisms of ethanol's actions in carcinogen activation, and alcohol-related cancers are extensively reviewed. This book is designed for the researcher trying to understand how alcohol causes cancer, as well as the clinician/epidemiologist wishing to know more about its role in human cancer incidence.
What people are saying - Write a review
We haven't found any reviews in the usual places.
The Role of Ethanol in Esophageal Carcinogenesis
Ethanol and Risk of Cancer of the Oral Cavity
Alcohol Effects on Anticancer Drug Metabolism
acetaldehyde activation acute ethanol alcohol consumption alcohol intake alcoholic beverages alcoholic liver disease anti-HCV antibodies anticancer drug antigen associated azoxymethane Biochem Biol Brechot Cancer Inst Cancer Res carcinogen carcinogenesis cellular chronic alcohol chronic ethanol consumption cirrhotics clearance Clin colon cyclophosphamide cytochrome P-450 cytochrome P-450 IIE1 demethylase development of HCC dietary dimethylnitrosamine dose drinkers drinking effect of alcohol Effect of chronic effects of ethanol enhanced enzyme esophageal cancer esophageal carcinoma ethanol-induced exposure fibrosis Garro Gastroenterology glutathione HBs.Ag HBs.Ag-negative HBs.Ag-positive HBV markers HBV-DNA hepatitis B virus hepatocellular carcinoma hepatocytes Hepatology human induced inhibition interaction lesions Lieber lipid peroxidation liver cells Mallory bodies methylation methylbenzylnitrosamine mice microsomal mutagen N-nitrosodimethylamine Natl NDMA nitrosamines nonsmokers Nutr oral cavity oxidation patients Pharmacol pharyngeal cancer pharynx prevalence procarcinogens protein rat liver rectal role Seitz serum Simanowski smoking synthesis tissue tobacco toxicity tumors viral virus DNA vitamin vitro vivo