Alcohol and the Gastrointestinal Tract
Victor R. Preedy, Ronald Ross Watson
Taylor & Francis, 1996 - Medical - 347 pages
This book covers all aspects of gastrointestinal tract problems caused by alcohol misuse. Opening chapters discuss epidemiology and the metabolism of alcohol and the liver's role in that process. Alcohol and acetaldehyde dehydrogenases, free radicals, and endocrine changes are discussed in detail. Recent advances in the pathophysiology of alcohol-induced disorders are summarized and many chapters detail techniques such as permeability and protein synthesis. Effects on specific organs, including the salivary glands, stomach, pancreas, and small intestine, are also discussed. All contributors and both editors are internationally recognized experts in their fields.
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Alcohol and Aldehyde Dehydrogenases in the Gastrointestinal Tract
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absorption acetaldehyde activity acute ethanol alcohol dehydrogenase alcoholic pancreatitis aldehyde ALDH amino acid Baraona Biochem Biol blebs blood brush-border Cancer carcinogenesis cell proliferation cholesterol chronic alcohol chronic ethanol consumption chronic pancreatitis cirrhosis Clin colonic concentrations cytoprotection damage decreased diarrhea diet dietary digestive Dinda disease dose effect of ethanol enterocyte enzyme epithelial cells epithelium esophageal ethanol administration ethanol metabolism ethanol-induced Exposure to Ethanol factors fatty acids free radicals function gastric emptying gastric mucosa Gastroenterol Gastroenterology gastrointestinal tract glucose hepatic histamine human increased induced inhibition inhibitor injury intake intestinal permeability intraluminal jejunal jejunum lactulose Lieber lipid peroxidation lipoproteins liver lumen luminal malabsorption mechanism mediated membrane microsomal microvascular motility mucosal muscle normal Nutr nutrients nutrition oxidation oxygen patients peptide perfusion Pharmacol Physiol prostaglandin protein synthesis role secretion sialadenosis small intestine stimulation stomach studies tissue toxic transport uptake villus core vitamin vitro vivo xanthine oxidase