Allergic Diseases and the Environment

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Erika Isolauri, W. Allan Walker
Karger, 2004 - Medical - 324 pages
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During the last two decades the increase in allergic diseases in children, such as atopic dermatitis and asthma, has been drastic. However, this is not true for the entire world: the incidence of allergies in children has risen only in developed countries. The observation of this socio-geographic discrepancy has led to careful study of the environmental differences that exist between the diverse settings in which children are born and has resulted in the so-called 'hygiene hypothesis': the 'sterility' of modern hospitals and birth places in the developed world might lead to a lack of microbial stimulation required for the development of a balanced mucosal immune response, including expansion of T-helper (Th) cell subsets that can mediate immune responses. Therefore, this workshop was held to consider in depth the environmental factors that influence the changing pattern of worldwide childhood allergy. This publication is a valuable source of knowledge and update for nutritionists, pediatricians, immunologists, microbiologists, as well as professionals concerned with preventive medicine.

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Contents

Changing Definitions of Allergy
27
The Changing Prevalence and Clinical Profile
33
Modulation of the Atopic
53
Copyright

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About the author (2004)

W. Allan Walker, M.D., is a professor of pediatrics and the director of the Division of Nutrition at Harvard Medical School. He is a recipient of the prestigious Murray Davidson Award for Excellence in Pediatric Nutrition from the American Academy of Pediatrics. Courtney Humphries is a professional writer specializing in health topics.

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