Allergic Diseases and the Environment

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Karger Medical and Scientific Publishers, 2004 - Medical - 48 pages
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During the last two decades the increase in allergic diseases in children, such as atopic dermatitis and asthma, has been drastic. However, this is not true for the entire world: the incidence of allergies in children has risen only in developed countries. The observation of this socio-geographic discrepancy has led to careful study of the environmental differences that exist between the diverse settings in which children are born and has resulted in the so-called 'hygiene hypothesis': the 'sterility' of modern hospitals and birth places in the developed world might lead to a lack of microbial stimulation required for the development of a balanced mucosal immune response, including expansion of T-helper (Th) cell subsets that can mediate immune responses. Therefore, this workshop was held to consider in depth the environmental factors that influence the changing pattern of worldwide childhood allergy. This publication is a valuable source of knowledge and update for nutritionists, pediatricians, immunologists, microbiologists, as well as professionals concerned with preventive medicine.
 

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Contents

The Changing Pattern of Clinical Aspects of Allergic Diseases
1
Changing Definitions of Allergy
27
The Changing Prevalence and Clinical Profile of Food Allergy in Infancy
33
Modulation of the Atopic Phenotype by Environmental Microbial Exposure
53
Is It a Th2Predominant Disease? Pro
69
The Induction of Immunoregulation Prevents the Development of Immunopathology in Chronic Helminth Infections and Allergy
97
Mechanisms Governing Non Responsiveness to Food Proteins
117
Oral Tolerance and Gut Maturation
133
Does BreastFeeding Protect from Allergies?
199
Protective Nutrients and Gastrointestinal Allergies
217
Identification of Probiotics and Prebiotics with Antiallergenic Properties1
251
Can We Prevent the Allergic Child from Becoming a Chronic Asthmatic Adult?
267
A Model for Allergy Prevention
285
Novel Approaches for the Nutritional Management of the Allergic Infant1
301
Concluding Remarks
315
Subject Index
319

The Role of Bacteria in the Development of Intestinal Protective Function
153
Ecology Physiology and Metabolic Potential of Intestinal Bacteria
179

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About the author (2004)

W. Allan Walker, M.D., is a professor of pediatrics and the director of the Division of Nutrition at Harvard Medical School. He is a recipient of the prestigious Murray Davidson Award for Excellence in Pediatric Nutrition from the American Academy of Pediatrics. Courtney Humphries is a professional writer specializing in health topics.

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