Alpha -adrenoceptors: Signal Transduction, Ionic Channels, and Effector Organs : Proceedings of the 9/10th [alpha]-adrenoceptors Conference, Tokyo, August 30-31, 1991
Motohatsu Fujiwara, Tsuneaki Sugimoto, Kyuya Kogure
Excerpta Medica, 1992 - Medical - 284 pages
Part of a series which presents the results of research on alpha-adrenoceptors. This volume focuses on the latest research on the structure, function and regulation of alpha-adrenoceptors, receptor-coupled ionic channels, and signal transduction and effectors of alpha-adrenoceptors.
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Role of phospholipid breakdown in signal transduction
Protein kinase C in transmembrane signaling cascade
Structure and function of the inositol 145trisphosphate receptor
13 other sections not shown
1-adrenergic receptors 1-adrenoceptors 5-methylurapidil activation adrenergic adrenergic receptor affinity agonists antagonists aorta aortic arachidonic acid artery Biochem Biol Chem brain bunazosin bupranolol c-fos Ca2+ channel calcium cardiac catecholamines Cell-attached Circ Res concentration contractile contraction coupling cyclase cytosolic desensitization diabetic diacylglycerol EDRF Endoh endothelium enhanced enzyme G proteins gene GTPyS heart hydrolysis hypertension hypertrophy increase incubated induced inhibited inhibitor inositol inotropic intracellular IP3 receptors ischemia isozyme Japan K+ channel KACh channel mechanism mediated membrane metabolites MLC phosphorylation molecular muscarinic receptor myocardial myocardium myocytes NDP kinase neuronal norepinephrine norepinephrine-induced pertussis Pharmacol phenylephrine phorbol ester phospholipase phosphorylation Physiol PI-PLC plasma positive inotropic effect prazosin pretreatment Professor protein kinase rabbit receptor subtypes regulation release response role second messengers sensitivity signal transduction smooth muscle cells stimulation tion tissues vascular smooth muscle ventricular VOC channel