Tuberculosis: New Insights for the Healthcare Professional: 2011 Edition

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ScholarlyEditions, Jan 9, 2012 - Medical - 323 pages
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Tuberculosis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Tuberculosis.

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Contents

Clinical Trials
Genetics
New tuberculosis data have been reported by ABS Silva and coauthors
Distinct genotypic profiles of the two major clades of Mycobacterium africanum
Highresolution melting curve analysis for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates
The nonmevalonate pathway of isoprenoid biosynthesis in Mycobacterium tuberculosis is essential and transcriptionally regulated by Dxs
Reports from World Health Organization add new data to research in Mycobacterium tuberculosis
embCAB sequence variation among ethambutolresistant Mycobacterium tuberculosis isolates without embB306 mutation
Mutation rates of spoligotypes and variable numbers of tandem repeat loci in Mycobacterium tuberculosis
Characterization of a Mycobacterium tuberculosis ESX3 conditional mutant essentiality and rescue by iron and zinc
Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms
Effects of tuberculosis race and human gene SLCO1B1 polymorphisms on rifampin concentrations
Overproduction and localization of Mycobacterium tuberculosis ParA and ParB proteins
Lsr2 is a nucleoidassociated protein that targets ATrich sequences and virulence genes in Mycobacterium tuberculosis
The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
mosR a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis

Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than paraaminosalic...
Research conducted at National Institute for Medical Research has updated our knowledge about Mycobacterium tuberculosis
Research from CC Cardoso and coauthors provides new data about tuberculosis
Research from M Verza and coresearchers in the area of tuberculosis therapy described
Strains of the East Asian WBeijing lineage of Mycobacterium tuberculosis are DosSDosTDosR twocomponent regulatory system natural mutants
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis
High Heritability of Antimycobacterial Immunity in an Area of Hyperendemicity for Tuberculosis Disease
Spoligotypebased comparative population structure analysis of multidrugresistant and isoniazidmonoresistant Mycobacterium tuberculosis complex c...
Research reports from Universidad Nacional Autonoma de Mexico provide new insights into tuberculosis cell biology
Scientists at Center for Infections release new data on tuberculosis
A new technique for obtaining whole pathogen transcriptomes from infected host tissues
Detection of rpoB katG and inhA gene mutations in Mycobacterium tuberculosis clinical isolates from Chongqing as determined by microarray
3Ketosteroid 9alphahydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis
Bacterial Genetic Signatures of Human Social Phenomena among Mtuberculosis from an Aboriginal Canadian Population
Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis a casecontrol association study
Studies from School of Biological Sciences in the area of genetics and tuberculosis described
Study data from J Abendroth and colleagues update understanding of life sciences
Study data from University of Paris Institute of Genetics and Microbiology update understanding of genetics and tuberculosis
Genetic Polymorphisms of Cytochrome P450 and Glutathione Stransferase Associated with Antituberculosis Druginduced Hepatotoxicity in Chinese ...
Elucidation of the functional metal binding profile of a CdIIPbII sensor CmtRSc from Streptomyces coelicolor
Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid
Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories
Mycobacterial outer membranes in search of proteins
Tuberculosis transmission patterns among Spanishborn and foreignborn populations in the city of Barcelona
Characterization of a betahydroxybutyrylCoA dehydrogenase from Mycobacterium tuberculosis
Comparison of restriction fragment length polymorphism with the polymorphic guaninecytosinerich sequence and spoligotyping for differentiation ...
Differences among sublineages of the EastAsian lineage of Mycobacterium tuberculosis in genotypic clustering
Influence of M tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis
Firstinman open clinical trial of a combined rdESAT6 and rCFP10 tuberculosis specific skin test reagent
Genetic susceptibility to different clinical forms of tuberculosis in the Peruvian population
Genetic analysis of extensively drugresistant Mycobacterium tuberculosis strains in Lisbon Portugal
Rapid methods for testing inhibitors of mycobacterial growth
Allelic Exchange and Mutant Selection Demonstrate that Common Clinical embCAB Gene Mutations Only Modestly Increase Resistance to Ethambut...
Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of ondemand nearpatient technology
Mycobacterium africanum is not a major cause of human tuberculosis in Cape Town South Africa
Combined realtime PCR and rpoB gene pyrosequencing for rapid identification of Mycobacterium tuberculosis and determination of rifampin resista...
Conservation of structure and proteinprotein interactions mediated by the secreted mycobacterial proteins EsxA EsxB and EspA
Mutations Found in the pncA Gene of Mycobacterium tuberculosis in Clinical Pyrazinamideresistant Isolates from a Local Region of China
Association between FokI polymorphism in vitamin D receptor gene and susceptibility to spinal tuberculosis in Chinese Han population
Lack of association between MD2 promoter gene variants and tuberculosis
Immunology
Studies from Universidade Federal de Juiz de Fora provide new data on tuberculosis
Delivery of rifampicinPLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis
Role of QuantiFERONTB gold interferon gamma inducible protein10 and tuberculin skin test in active tuberculosis diagnosis
Comparison of the pharmacokinetics of two dosage regimens of linezolid in multidrugresistant and extensively drugresistant tuberculosis patients
Human monocyte differentiation stage affects response to arachidonic acid
Role of TLR2and TLR4mediated signaling in Mycobacterium tuberculosisinduced macrophage death
Mycobacterium tuberculosis employs Cpn602 as an adhesin that binds CD43 on the macrophage surface
Rational design of multiple TB antigens TB104 and TB104Ag85B as subunit vaccine candidates against Mycobacterium tuberculosis
Chemokine gene expression in lung CD8 T cells correlates with protective immunity in mice immunized intranasally with Adenovirus85A
Nasal associated lymphoid tissue NALT contributes little to protection against aerosol challenge with Mycobacterium tuberculosis after immunisation ...
Partial and ineffective activation of Vgamma9Vdelta2 T cells by Mycobacterium tuberculosisinfected dendritic cells
Antituberculosis immunity induced in mice by vaccination with Mycobacterium smegmatis overexpressing Antigen 85B is due to the increased influ...
Development of a skin test for bovine tuberculosis for differentiating infected from vaccinated animals
Identification of a novel cytotoxic T lymphocyte epitope from CFP21 a secreted protein of Mycobacterium tuberculosis
Risk and Prevention
Surgery
Therapies and Treatments
Tuberculosis global approaches to a global disease
Early bactericidal activity and pharmacokinetics of PA824 in smearpositive tuberculosis patients
Mycobacterium tuberculosis ESX1 systemsecreted protein ESAT6 but not CFP10 inhibits human Tcell immune responses
Lactoferrin enhances efficacy of the BCG vaccine comparison between two inbred mice strains C57BL6 and BALBc
New susceptibility breakpoints for firstline antituberculosis drugs based on antimicrobial pharmacokineticpharmacodynamic science and population ...
Therapeutic drug monitoring for slow response to tuberculosis treatment in a state control program Virginia USA
Adjuvants induce distinct immunological phenotypes in a bovine tuberculosis vaccine model
Vaccines
Helminth coinfection does not affect therapeutic effect of a DNA vaccine in mice harboring tuberculosis
Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85BESAT6 fusion protein
Additional Research
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