Alternatives to Blood Transfusion in Transfusion Medicine

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Alice Maniatis, Jean-François Hardy, Phillipe van der Linden
John Wiley & Sons, Jul 5, 2011 - Medical - 608 pages
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Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.

Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:

  • Argon beam
  • Cell saver
  • Harmonic scalpel
  • Normovolemic haemodilution
  • Synthetic erythropoietin
  • Antifibrinolytics
  • Recombinant factor VIIa
  • Advanced monitoring of hemostasis
  • Intravenous iron

The new edition is a key reference source for all those involved in the practice of blood management and conservation.


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CHAPTER 23Efficacy and Safety of Recombinant
Efficacy ofrFVIIafor the treatment of excessive
Role of HemoglobinHematocrit
Effects onpotency and qualityofproduct Toxicology and neoantigens
CausesDiagnosis and Management
CurrentStatus of Perisurgical
Erythropoietin and Iron Therapy Patients with Renal Failure

CHAPTER 13Choiceof a Synthetic Colloid
CHAPTER 19Tissue Oxygenation and Blood
Availableand developing technologies Clinicaltrials
Pharmacology of Intravenous Fluids
Thrombelastography andthrombelastometry reveal hypocoagulability
CHAPTER 12Hydroxyethyl
Nephrotoxicity associated withfluid replacement
CHAPTER 20Anemia and Cardiovascular Disease
Monitoring of Hemostasis in
CHAPTER 22Antifibrinolytics in OpenHeart Surgery
The 1030 rule
Perfluorocarbon Emulsions
Adjunctive Strategies toImpact Blood
Anesthetic Techniques to Reduce
Acute Normovolemic Hemodilution
Fact or Fallacy?
Intraoperative and Postoperative Cell
Management of anemia
Conclusions and recommendations
CHAPTER 40RedBlood Cell Transfusions and Alternatives toTreatthe Anemia
Transfusion Alternatives in Orthopedic
CHAPTER 42Transfusion Alternatives in Obstetrics
Blood Transfusions Jehovahs
The Cost and CostEffectiveness
CHAPTER 47CostEffectiveness of Pharmacological
CHAPTER 25Calculation ofBlood Loss

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About the author (2011)

Professor Alice Maniatis, Haematology Department of Internal Medicine, University of Greece, Athens, Greece and former President of Network for Advancement of Transfusion Alternatives (NATA).

Dr Jean-Francois Hardy, Department of Anesthesia, Montreal Heart Institute, Quebec, Canada and on the Board of Directors of NATA.

Dr Phillipe van der Linden, Department of Anesthesiology and Intensive Care, Brussels, Belguim and on the Board of Directors of NATA.

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