Amino Acids, Peptides and Proteins, Volume 36
In an ever-increasing domain of activity, Amino Acids, Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Comprising a comprehensive review of significant developments at this biology/chemistry interface, each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters, ranging from current trends in their synthesis and conformational and structural analysis, to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters, whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas, allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries, and at the biology/chemistry interface in academia will find this an indispensable reference source. Volume 36 covers literature published during 2003.
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Analogue and conformational studies on peptides hormones and other
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acid derivatives activity affinity agents alkylation amide amines amino acids analogues antagonists antibacterial antimicrobial aromatic asymmetric Biochem Biol biological Biomol Bioorg bond carboxyl catalyst cell Chem chemistry Chen chiral chromatography CO2H compounds conformation conjugates coordination copper(II coupling Cu(II cyclic peptides cyclo cysteine developed diastereoselective dipeptide drug enantiomerically enantiomers enantioselective enzyme esters Fmoc formation fragments functional glycopeptides inhibition inhibitors integrin interaction investigated ligands linker macrocyclic membrane metal binding metal complexes metal ions method moiety molecular molecules N-terminal nickel(II novel o-amino oxidation Pept peptides containing peptidomimetic phase potent precursor prepared protease Proteins reaction reagent receptor reported residues resin reviewed ring Scheme selective sequence side chains solid-phase solution somatostatin spectroscopic stability stereoselective structure studied substituted substrate synthesis synthesized telomerase ternary complexes Tetrahedron Lett thiol toxins vancomycin vitro Wang yields Zhang