Amino Acids, Peptides and Proteins, Volume 31
J S Davies
Royal Society of Chemistry, Nov 8, 2000 - Reference - 462 pages
In an ever-increasing domain of activity Amino Acids Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 31 provides a review of literature published during 1998. Comprising a comprehensive review of significant developments at this biology/chemistry interface each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters ranging from current trends in their synthesis and conformational and structural analysis to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries and at the biology/chemistry interface in academia will find this an indispensable reference source.
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Amino Acids 1
Heteroaromatic Groupings in Sidechains
24 other sections not shown
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a-amino acid derivatives acid esters Acta activity acyl affinity agonist alanine aldehyde alkylation amide amination amino acids analogues antagonists aqueous aspartic Asymmetry atoms Biochem Biol Bioorg Bioorg.MedChem.Lett bond C-terminal carboxylate catalysed cathepsin cell chelating Chem Chen Chim chiral CO2H complexes compounds conformation coordination copper(II cyclic peptides cysteine Dalton Trans deprotonation dimeric dipeptide domain enantiomer enantioselective enzyme esters Fmoc formation formed give glutamic glycine homochiral human hydrolysis IC50 values inhibited inhibitors Inorg interactions J.Am.Chem.Soc J.Chem.Soc J.MedChem J.Org.Chem J.Pept.Res less potent ligands metal binding metal ions method methyl moiety molecules N-protected nickel(II nitrogen non-peptide oxidation palladium(II Peptide Sci peptides containing Perkin Trans Pharmacol platinum(II prepared protease protein protonated reaction Reagents receptor residues resin ring route Sar1 Scheme Schiff base selective sequence serine side-chain solution species studies substrate Synlett synthesis synthon ternary Tetrahedron Lett thiol tion tripeptides tyrosine Wang X-ray Zhang zinc(II