Amino Acids, Peptides and Proteins, Volume 30
J S Davies
Royal Society of Chemistry, Oct 27, 1999 - Reference - 414 pages
In an ever-increasing domain of activity Amino Acids Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 30 provides a review of literature published during 1997. Comprising a comprehensive review of significant developments at this biology/chemistry interface each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters ranging from current trends in their synthesis and conformational and structural analysis to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries and at the biology/chemistry interface in academia will find this an indispensable reference source.
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Chemical Synthesis and Resolution of Amino Acids
Physicochemical Studies of Amino Acids
21 other sections not shown
Other editions - View all
a-amino activity affinity agonist aldehyde alkylation amide amination amino acids analogues angiotensin antagonist antibacterial Antibiot aqueous assay Asymmetry azetidinones binding Biochem Biol Bioorg Bioorg.Med.Chem.Lett bombesin bond bradykinin C-terminal carbapenems carboxylic catalysed CCKA CCKB cells cephalosporin cephem Chem Chem.Abs Chem.Soc chemistry chiral conformation cyclic peptides cycloaddition derivatives diastereoselective dipeptide disulfide enantiomers enantioselective enzyme esters Fmoc formation give glycine glycopeptides Heterocycles homochiral hormone HPLC human hydrolysis IC50 values imines inhibited inhibitors interaction J.Am.Chem.Soc J.Chem.Soc J.Org.Chem J.Pept.Res Kj values less potent ligands membranes methyl mg kg-1 moiety nociceptin non-peptide oral oxidation P-lactam P-lactamase P-turn penicillin Pept peptides containing Perkin phage Pharmacol potent compounds precursor prepared protease protein reaction Reagents receptor receptor subtypes reported residue ring route SAR studies Scheme selective sequence serine side chain solid phase SPPS structure substituted substrates Synlett Tetrahedron Lett thrombin Trans vivo yield