Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides

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John Wiley & Sons, Feb 13, 2013 - Science - 508 pages
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This is the last of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. 

Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins.

The practical value of each volume is heightened by the inclusion of experimental procedures.

 

The 5 volumes cover the following topics:

Volume 1: Origins and Synthesis of Amino Acids

Volume 2: Modified Amino Acids, Organocatalysis and Enzymes

Volume 3: Building Blocks, Catalysis and Coupling Chemistry

Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

Volume 5: Analysis and Function of Amino Acids and Peptides

 

Volume 5 of this series presents a wealth of methods to analyze amino acids and peptides. Classical approaches are described, such as X-ray analysis, chromatographic methods, NMR, AFM, mass spectrometry and 2D-gel electrophoresis, as well as newer approaches, including Surface Plasmon Resonance and array technologies.

 

Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage.

Further information about the 5 Volume Set and purchasing details can be viewed here.

 

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Contents

Volume 5 Analysis and Function of Amino Acids and Peptides 1 Mass Spectrometry of Amino Acids and Proteins
1
Volume 5 Analysis and Function of Amino Acids and Peptides 2 XRay Structure Determination of Proteins and Peptides
51
Volume 5 Analysis and Function of Amino Acids and Peptides 3 Nuclear Magnetic Resonance of Amino Acids Peptides and Proteins
97
Volume 5 Analysis and Function of Amino Acids and Peptides 4 Structure and Activity of NMethylated Peptides
155
Volume 5 Analysis and Function of Amino Acids and Peptides 5 HighPerformance Liquid Chromatography of Peptides and Proteins
167
Volume 5 Analysis and Function of Amino Acids and Peptides 6 Local Surface Plasmon Resonance and Electrochemical Biosensing Systems for An...
211
Volume 5 Analysis and Function of Amino Acids and Peptides 7 Surface Plasmon Resonance Spectroscopy in the Biosciences
225
Volume 5 Analysis and Function of Amino Acids and Peptides 8 Atomic Force Microscopy of Proteins
249
Volume 5 Analysis and Function of Amino Acids and Peptides 9 Solvent Interactions with Proteins and Other Macromolecules
277
Volume 5 Analysis and Function of Amino Acids and Peptides 10 Role of Cysteine
361
Volume 5 Analysis and Function of Amino Acids and Peptides 11 Role of Disulfide Bonds in Peptide and Protein Conformation
395
Volume 5 Analysis and Function of Amino Acids and Peptides 12 Quantitative Mass SpectrometryBased Proteomics
419
Volume 5 Analysis and Function of Amino Acids and Peptides 13 TwoDimensional Gel Electrophoresis and ProteinPolypeptide Assignment
439
Volume 5 Analysis and Function of Amino Acids and Peptides 14 Bioinformatics Tools for Detecting PostTranslational Modifications in Mass Spectr...
463
Volume 5 Analysis and Function of Amino Acids and Peptides Index
477
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About the author (2013)

Andrew Hughes is a Reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post-doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley's group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.

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