An Atlas of Drosophila Genes: Sequences and Molecular Features
Drosophila, the common fruit fly, is the most extensively studied of all organisms from the standpoint of genetics and cytology. This atlas summarizes what is known about the approximately 100 Drosophila genes for which the complete nucleotide sequence is known. Each entry includes a description of the gene's molecular organization and expression, the complete nucleotide and amino acid sequences, maps of interesting structures, highlights of functional features and promoter regulatory regions, and selected references to the primary literature. A separate section of the atlas considers different aspects of gene organization as they occur in the Drosophila genome. Topics covered include size correlations among various genetic elements, splicing signals, translation initiation signals, and codon bias. The work represents a new milestone in summarizing current information and making it easily accessible to geneticists and biologists.
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Acids Res actin activity alleles amino acids bases bicoid binding sites Biol blastoderm bp upstream branchpoint cDNA cDNA sequence Chromosomal Location cis-acting cluster coding region codon usage complex cuticle protein Dataset define dehydrogenase detected Developmental Pattern distal DNA-binding Drosophila embryo Drosophila melanogaster EMBO embryo encodes exon expected mRNA length Expression Open reading function fushi tarazu gastrulation gene expression Gene Organization Genes Dev genes in Drosophila Genetics germ band heat shock heat shock protein homeodomain instar introns kinase Krüppel larval mammalian Map Position Molecular mRNA mutations nuclear nucleotides Nüsslein-Volhard Open reading frame Organization and Expression parasegments polyadenylation posterior Primer extension promoter proximal receptor regulation regulatory elements S1 mapping segmentation gene Sgs3 Sgs8 snRNP splice site splice sites spliceosome Spradling stages start codon stripes Structure TATA box transcription initiation Ultrabithorax yolk protein
Page 377 - Kozak, M. (1986). Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292.