An Introduction to Clinical Pharmaceutics

Front Cover
Pharmaceutical Press, 2010 - Medical - 179 pages
This unique textbook considers the role of basic pharmaceutics in determining or modifying clinical outcomes and in explaining the behaviour of medicines in the body, including adverse reactions due to formulations and excipients. An Introduction to Clinical Pharmaceutics covers recent developments such as personalised therapies and nanotechnology. All of the principles underpinning clinical pharmaceutics are supported using relevant examples from recent literature and clinical case studies, including issues of: formulation and excipients; surface tension; rheology; solubility; crystallisation and precipitation; aggregation; absorption. Examples and implications of each phenomenon are discussed with a reminder of the underlying pharmaceutics. This book is aimed at undergraduate pharmacy students, those on taught Masters courses of clinical and hospital pharmacy, and new practitioners who require an updating on the relevance of the subject that is virtually unique to pharmacy.
 

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Contents

1 What is clinical pharmaceutics?
1
2 Excipients Not always inert
27
3 Thinking chemically
41
4 Looking at formulations
69
5 Adverse events and formulations and devices
101
6 Paediatric geriatric and special formulations
121
7 Generic medicines Conventional drugs and biologicals
133
8 The future Delivery systems for modern therapeutics
151
Index
173
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