An Introduction to Vitamins, Minerals and Oxidative Stress: The Role of Micronutrients and Reactive Oxygen Species in Normal and Pathological Processes

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Universal-Publishers, 2008 - Health & Fitness - 216 pages
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This book presents in simple and concise terms the biological functions of vitamins and minerals, what makes them essential to life and why they must be replenished daily from food. The best food sources for these micronutrients and the daily recommended intakes of vitamins and minerals are also presented. Information on these important micronutrients is all presented in one place (Part I) as opposed to the current text books where it is scattered throughout the text, making its retrieval tedious and time-consuming. In addition, the trace elements get an adequate coverage in contrast to the current texts. The second part introduces the reader to the concept of oxidative stress and the role of free radicals (mainly of oxygen and nitrogen) in the regulation of several biological processes like cellular redox homeostasis, programmed cell death and aging as well as their involvement in many pathological conditions such as cardiovascular disease, cancer, autoimmune and neurodegenerative diseases. Readers will also learn how reactive molecular species are generated, what their targets are and how cells defend themselves against the deleterious action of free radicals. Despite the growing interest in the research of free radicals involvement in human pathology the current text books treat the subject only sparingly. Our text addresses this issue by giving the topic the attention it deserves.
 

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Contents

Vitamins and Minerals
13
Vitamins
19
Minerals
69
Absorption of Vitamins and Minerals
91
Daily Requirements
93
Biological Oxidation and Oxidative Stress
97
Free Radicals Promoters of Oxidative Stress
105
b Generation of free radicals
108
e Oxidative stress and disease
136
Defense Mechanisms Against Oxidative Stress
141
b Enzymatic
153
c Nonenzymatic
154
Free Radicals and Programmed Cell Death
163
Oxidative Stress and Aging
179
Health Benefits of Keeping Oxidative Stress Under Control
193
Addendum
201

c Targets for the free radicals in the body
117
d Biological consequences of lipid peroxidation
135

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