Anatomy of a Scientific Discovery
"An international race during the 1970s among scientists in the U.S. and Scotland to isolate endorphinsnatural, morphine-like substances present in the brainis recounted in clear and colorful detail by science writer Goldberg (coauthor of Flowers in the Blood). He gives an account of the discovery (by the team of Hans Kosterlitz and John Hughes, in a poorly funded lab in Aberdeen) of a nonaddictive narcotic chemical in pigs' brains, and then follows with a contrasting account of the high-tech research conducted by scientists at American universities on opiate receptors and experiments designed to stimulate natural pain-blocking, much of the American effort motivated by the need to combat heroin addiction. In 1976, the controversy-fraught laboratory competition was superceded by the race among drug companies to develop the most successful of the 20 types of opiate peptides; the prize would be domination of a market serving an estimated 20 million chronic pain sufferers in the U.S. alone. While some researchers have sought inconclusively to establish a relationship between endorphins and mental illness, others have focused on a proposed linkage between endorphins and pleasure, learning, stress and sexual response." -- This text refers to the Hardcover edition.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Other editions - View all
Aberdeen active addicts Airlie House amino acid animals announcement Avram Goldstein Barry Morgan began Belluzi beta-endorphin Bloom C-fragment called Candace Pert Catlin chemical clinical Cocoyoc colleagues compound conference deferens discovery doses drug company dynorphin effects endogenous opiate endorphin levels endorphins enkephalin experiments extract felt formula Frederickson gland going Graeme Henderson guinea pig ileum Hanna Hauser Heinz Lehmann Hopkins hormone Howard Morris Huda Akil Hughes and Kosterlitz human ileum injected John Hughes John Hughes's Kosterlitz Lars Terenius later Li's Liebeskind Lilly Linda Fothergill lipotrophin Marishal College McKnight meeting mental illness Met-enkephalin metkephamid molecular months Morgan morphine morphinelike naloxone Nathan Kline Nature opiate receptors pain relief painkiller paper Pasternak patients peptides pharmaceutical pharmacology pig brains pituitary produced protein rats recalls Roger Guillemin Romer samples Sandoz schizophrenia scientific scientists seemed Smyth Solomon Snyder Stein Substance synthetic talk Terry Smith tion Udenfriend weeks