Androgen Excess Disorders in Women
Ricardo Azziz, John E. Nestler, Didier Dewailly
Lippincott-Raven, 1997 - Health & Fitness - 831 pages
This is a review of research findings on the aetiology, pathophysiology, clinical manifestations and consequences of androgen excess disorders in women, and the methods available for its diagnosis and treatment. Coverage includes information on the major inherited androgen excess disorders: the adrenal hyperplasias and the severe insulin-resistant hyperandrogenic syndromes.
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Normal Regulation of Adrenal Androgen Production
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21-hydroxylase 5a-reductase abnormalities acne ACTH activity adrenal androgen adrenal hyperplasia adrenarche adrenocortical androgen excess androgen levels androgen production androgen secretion androstenedione anovulation associated Azziz basal Chapter circulating Clin Endocrinol Metab clinical concentrations cortisol Cushing's Cushing's syndrome cycle decrease deficiency dehydroepiandrosterone Dewailly dexamethasone DHEAS diagnosis disease disorder drogen effects elevated endocrine Endocrinology enzyme estradiol estrogen female Fertil Steril fetal follicular free testosterone function gene genetic globulin glucocorticoid glucose GnRH gonadotropin granulosa cells growth factor hair follicle hair growth hirsute women hirsutism human hyperandrogenic women hyperandrogenism hyperinsulinemia IGF-I increased inhibin inhibition insulin receptor insulin resistance insulin-like growth luteinizing menstrual metabolism mutations NCAH Nestler normal obese Obstet Gynecol ovarian androgen ovarian hyperandrogenism ovulation ovulatory PCOS PCOS patients pituitary plasma polycystic ovary syndrome prenatal protein pubarche response role serum SHBG steroid steroidogenesis steroidogenic stimulation studies suppression testosterone therapy tion tissue treatment tumors virilization women with PCOS