Androgenetic Alopecia: Modern Concepts of Pathogenesis and Treatment
Until now, the general belief has been that premature baldness (male pattern bald ness: M.P.B., or androgenetie alopeeia) is a hereditary eondition that progresses with age and for which there is no eure. If the father is bald, it is assumed that the ehild may also be destined to be bald sometime in the future. The existing theory throughout the world is that the eentral portion of the hair follicle is the hair root, and hair ean never regrow if the hair root has been removed. Dr. Inaba has introdueed a new theory that the eentral portion of the hair folliele is not only the hair root but the upper isthmal portion elose to the duet opening of the sebaeeous gland. This is a totaUy new understanding of the hair growth mechanism and the hair eyele. In his experienee in the surgieal removal of the sweat glands, whieh also removes the hair root, Dr. Inaba has found inereasing evidenee that hair regrows if the sebaeeous gland is left intaet.
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Structure of Skin and Hair Follicles
Preparation of Thick Tissue Specimens
Generation and Growth of Human Hair
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50-reductase acid activity agents alopecia areata anagen stage androgenetic alopecia artificial hair atrophied axillary hair bulbous peg stage bulge catagen ceous gland coarse hair connective tissue dermal papilla dermis duct opening enzyme epidermis epithelial cells estrogen fiber flap follicular formation formed frontal germinal layer hair bulb hair cycle hair follicle hair germ stage hair growth hair loss hair matrix hair peg stage hair regeneration hair root hair-bearing graft hairline histological implantation Inaba and Inaba inner root sheath keratinization lipid lower portion male pattern baldness mass of mesenchymal melanin granules melanocytes mesenchymal cells method minoxidil multilobular nerve observed occipital outer root sheath patients protein punch region scalp hair scar sebaceous gland sebaceous isthmus sebum single hair skin surface stem cells studies subcutaneous suture telogen follicle telogen hair follicle telogen stage terminal hair testosterone thick tissue tion transplanted upper isthmal portion vellus hair vibrissa young hair