Animal Models of Human Disease

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Academic Press, Mar 4, 2011 - Science - 550 pages
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Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. This volume reviews the latest research and developments in this field.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

 

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Contents

Modeling Human Prostate Cancer in Genetically Engineered Mice
1
Modeling Cancers in Drosophila
51
Probing Human Cardiovascular Congenital Disease Using Transgenic Mouse Models
83
Dissection of Cardiovascular Development and Disease Pathways in Zebrafish
111
Drosophila Models of Cardiac Disease
155
Animal Models of Retinal Disease
211
Toward a Better Understanding of Human Eye Disease Insights From the Zebrafish Danio rerio
287
800 Facets of Retinal Degeneration
331
Animal Models of Glycogen Storage Disorders
369
Modeling Disorders of Fatty Acid Metabolism in the Mouse
389
Genetic Mouse Models of Neurodegenerative Diseases
419
Demise of the Flies Why Drosophila Models Still Matter
483
Watching Worms Whither Modeling Neurodegeneration in C elegans
499
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