Annual Reports in Medicinal Chemistry, Volume 40
Annette M. Doherty
Elsevier, Dec 19, 2005 - Medical - 558 pages
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.
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II Cardiovascular and Metabolic Diseases
III Inflammatory Pulmonary and Gastrointestinal Diseases
IV Cancer and Infectious Diseases
V Topics in Biology
VI Topics in Drug Design And Discovery
VII Trends and Perspectives
Cumulative NCE Introduction Index 19832004
Cumulative NCE Introduction Index 19832004 By Indication
44th ICAAC abarelix Abstract acid affinity agents analogs antibiotic antibody anticancer antifungal antihypertensive antineoplastic antiviral ARMC VOL assay azacitidine BACE BBB permeation Bcl-XL binding Biochem Biol biological biomarkers Bioorg brain cancer CAS Registry CB1 antagonists cells CETP Chem chemical tools Cl Cl Clin clinical trials compounds constitutive activity Curr CXCR3 demonstrated derived diabetes disease dose drug discovery duloxetine effects efficacy enzyme erlotinib everolimus function gemifloxacin glucose GPCR human increase infection inhibition inverse agonists kinase Lett ligands logBB MEDICINAL CHEMISTRY metabolic metabonomics mice microbicides models molecular nail plate Nucl onychomycosis Opin Patent pathway PDE4 pemetrexed peptide pharmaceutical pharmacokinetic Pharmacol Phase plasma protein rats recently receptor reduced rimonabant screening selectivity small molecule sodium strontium ranelate structural genomics studies subtypes Ther therapeutic therapy toxicity treatment TRPV1 tumor vitro vivo Wang XIAP ximelagatran Zhang
Page xiii - As in past volumes, annual updates have been limited only to the most active areas of research in favor of specifically focussed and mechanistically oriented chapters, where the objective is to provide the reader with the most important new results in a particular field. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design as well as the critical interfaces among these disciplines.