Annual Update in Intensive Care and Emergency Medicine 2012

Front Cover
Jean Louis Vincent
Springer Science & Business Media, Mar 6, 2012 - Medical - 845 pages
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The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
 

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Contents

Common Abbreviations
1
I Mechanisms of Sepsis and Critical Illness
2
Insights from Epigenetics
3
The Nervous System and Inflammation
12
The mHLADR System in the Critically Ill
19
Gut Microbiome and Host Defense Interactions during Critical Illness
29
II Metabolomics
41
The Metabolomic Approach to the Diagnosis of Critical Illness
43
The Ability of Red Blood Cell Transfusions to Reach the Microcirculation
431
Transfusionrelated Pulmonary Complications
441
XI Pulmonary Edema
459
Confounders in the Diagnosis of Pulmonary Edema in Surgical Patients
461
Neurogenic Pulmonary Edema
471
XII Emergencies
481
Elemental or Detrimental?
483
Afferent Limb of Rapid Response System Activation
494

Focus on Exhaled Air
53
III Sepsis Management
63
Cardiovascular Effects of Norepinephrine in Septic Shock
65
Vasopressin Therapy in Septic Shock
76
Antimicrobial Peptides and their Potential Application in Inflammation and Sepsis
85
Hypogammaglobulinemia in Sepsis
98
Is Procalcitonin the Answer?
109
Methods and Results
116
IV Endocrine Support
125
Traps and Tricks
127
Could They Have a Rosy Future in Critical Care?
138
V Acute Respiratory Distress Syndrome
147
The Complex Interaction between Sepsis and Lung Injury
149
Biomarkers of Acute Lung Injury
160
Role of the ReninAngiotensin System in ARDS
171
The Rise and Fall of βAgonists in the Treatment of ARDS
182
Molecular Mechanisms and Therapeutic Opportunities
194
VI Respiratory Support
205
Noninvasive Ventilation Outside the ICU
207
Dyspnea in the Mechanically Ventilated Patient
219
How to Improve Oxygenation before Intubation in Patients at Risk
228
Position and the Compromised Respiratory System
238
VII Pneumonia
251
Severe Communityacquired Pneumonia
253
Empiric Therapy of Grampositive Bloodstream Infections and Pneumonia
264
Oral Biofilms Systemic Disease and Pneumonia
278
Novel Preventive Strategies for Ventilatorassociated Pneumonia
289
Viralassociated Ventilatorassociated Pneumonia
299
VIII Fungal Infections
309
Early Recognition of Invasive Candidiasis in the ICU
311
Management of Invasive Candidiasis in the Critically Ill
324
Use of Antifungal Drugs during Continuous Hemofiltration Therapies
337
IX Hemodynamic Optimization
345
Guytonian Approach to the Circulation
347
A Way to Individual Goals
357
Monitoring Protocolized Care and Timing
368
A Manual for Bedside Use
383
X Fluids and Blood Transfusion
391
The Meaning of Fluid Responsiveness
393
Respiratory Variation in the Perioperative and Critical Care Settings
402
Think Microcirculation
412
Human Albumin in the Management of Complications of Liver Cirrhosis
421
Bradykininmediated Angioedema
504
XIII Cardiac Arrest
517
Controlled Oxygenation after Cardiac Arrest
519
Is There Still a Place for Vasopressors in the Treatment of Cardiac Arrest?
535
Cerebral Blood Flow after Cardiac Arrest
545
Whats Most Important for a Good Outcome?
556
XIV Pathogenesis of AKI
567
Role of Leukocytes in the Pathogenesis of Acute Kidney Injury
569
The Cardioabdominorenal Syndrome
577
XV Diagnosis of AKI
589
A Novel Paradigm
591
Not There Yet
597
Possible Role of NGAL as an Early Renal Biomarker
609
NGAL Curve for the Early Diagnosis of AKI in Heart Failure Patients
618
Urine Output and the Diagnosis of Acute Kidney Injury
628
XVI Management of AKI
641
The 5 B Approach
643
Coupled Plasma Filtrationadsorption
653
XVII Nutrition
659
Best Timing for Energy Provision during Critical Illness
661
Pharmaconutrition with Selenium in ICU Patients
672
XVIII Trauma
687
A New Understanding of Coagulopathy in Trauma
689
Diagnosis of Occult Bleeding in Polytrauma
699
Mitochondrial Dysfunction after Traumatic Brain Injury
710
The First 24 Hours after Severe Head Trauma
722
XIX Neurological Aspects
733
Brain Tissue Oxygen Monitoring in Neurocritical Care
735
Quantitative EEG for the Detection of Brain Ischemia
746
Does it Exist?
759
XX Sedation
769
Comparative Efficacy and Safety of Sedative Agents in Severe Traumatic Brain Injury
771
Optimizing Comfort while Maximizing Systemic and Neurological Function
783
XXI Management Method and Morale
795
Prehospital Care and Orientation of Critically Ill Geriatric Patients
797
Total Rehabilitation of the Critically Ill
803
Physician Heal Thyself
811
Designing a Safer Intensive Care Unit
819
Challenges in Implementing Evidencebased Medicine
828
Subject Index
837
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