Anticancer Agents: Frontiers in Cancer Chemotherapy, Volume 796

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Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann, American Chemical Society. Division of Organic Chemistry, American Chemical Society. Division of Medicinal Chemistry, American Chemical Society. Meeting
American Chemical Society, 2001 - Medical - 364 pages
Describes cutting edge approaches in the development of anticancer agents for chemotherapy. These new and interdisciplinary approaches are aimed at the development of tumor specific anticancer agents while increasing the potency against drug-resistant tumors. The volume includes an overview of new paradigms for cancer drug discovery and development by NCI, new generation cytotoxic agents, mechanism based enzyme inhibitors as anticancer agents, anti-angiogenesis agents, antitumor vaccines, and tumor activated prodrugs using immunoconjugates of monoclonal antibodies with cytotoxic agents.

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Evolutionary Biosynthesis of Anticancer Drugs
Some Recent Developments in the Synthesis and Structure
New Generation Taxoids and Hybrids of MicrotubleStabilizing

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About the author (2001)

Iwao Ojima is at State University of New York at Stony Brook. Gregory D. Vite is at Briston Myers Squibb. Karl-Heinz Altmann is at Novartis Pharmaceuticals.

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