Anticholinergic Agents in the Upper and Lower Airways

Front Cover
Sheldon Spector
CRC Press, Jun 4, 1999 - Medical - 240 pages
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This comprehensive collection discusses anticholinergic agents, integrating the treatment of rhinitis, the common cold, and asthma in the upper and lower airways, while updating the latest therapeutic practices.
Features assessments of soon-to-be-available medications!
Written by expert allergists and pulmonologists as an exploration of the clinical application of antimuscarinics, Anticholinergic Agents in the Upper and Lower Airways
  • explores the common triggers and pathogenesis of the upper and lower airways, including pathogenic mechanisms that cause allergies
  • covers hyperresponsiveness and the M2 and M3 receptors
  • considers the interactions of muscarinic receptors with other substances such as protein kinase C, cytokines, and growth factors that magnify the receptors' effects
  • analyzes bronchodilators, bronchomotor tone, and reflex bronchospastic mechanisms
  • assesses antimuscarinic drugs as treatment for acute asthma attacks
  • reviews the use of anticholinergic agents to treat rhinorrhea and upper respiratory infections
  • surveys data regarding the combination of beta agonists and antimuscarinics
  • evaluates the future of tiotropium bromide as a bronchodilator
  • focuses on the subspecialties of allergy and chest medicine
  • examines new work regarding the interaction of viruses and the muscarinic receptor
  • and more!
    Containing over 700 references to facilitate further study, Anticholinergic Agents in the Upper and Lower Airways is a thorough, multidisciplinary reference especially relevant to clinical immunologists and allergists, pulmonologists, physiologists, lung biologists, family and general practitioners, internists, pediatricians, and medical students in these disciplines.
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    Contents

    1 Basics of Muscarinic Physiology
    2
    2 Airway Muscarinic Receptors
    26
    Part Two APPLIED CLINICAL RESEARCH
    48
    3 Anticholinergic Agents as Bronchodilators
    49
    4 Anticholinergic Drug Therapy in the Management of Acute Severe Asthma
    62
    5 Use of Anticholinergics in Perennial
    72
    6 Pathogenesis and Treatment of Upper Respiratory Infections
    83
    7 Anticholinergics in Combination Bronchodilator Therapy in COPD
    97
    8 Tiotropium Ba 679
    112
    9 Historical Aspects of Medicinal Uses of Antimuscarinics
    127
    10 Interaction of Virus with the Muscarinic Receptor
    139
    Author Index
    154
    Subject Index
    184
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