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MechanismSpecific Pathways for New Antiepileptic Drug Discovery
The National Institutes of Health Anticonvulsant Drug
Pharmaceutical Industry Screening for New Antiepileptic Drugs
22 other sections not shown
absence seizures acid adenosine adults AMPA animal antagonists anticonvulsant anticonvulsant drugs antiepileptic drugs assessment baseline benzodiazepine brain carbamazepine channels Clin clinical trials cognitive complex partial seizures compounds concentrations currents dosage form dose double-blind drug development drug interactions duration efficacy enzyme epilepsy Epilepsy Res epileptic evaluation fects felbamate GABA GABAa receptors gabapentin glutamate human increase induced infantile spasms inhibition inhibitor investigators lamotrigine Leppik levels Mattson RH mazepine mechanism of action ment metabolism metabolite mg/d mg/kg Neurology neurons NMDA receptor oxcarbazepine partial epilepsy patients pediatric pharma pharmacodynamic pharmacokinetic Pharmacol Pharmacology phase phenobarbital phenytoin placebo plasma potential protocol reduction refractory risk seizure activity seizure frequency seizure rate seizure types seizure-free side effects spike-and-wave status epilepticus syndrome Ther therapeutic tiagabine tients tion tive tonic-clonic seizures Topiramate toxicity treat treatment trial design valproate vigabatrin women Zonisamide