Antioxidants in Diabetes Management

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Peter Rosen, Hans J. Tritschler, Glenn A. King, Angelo Azzi
CRC Press, Feb 18, 2000 - Medical - 376 pages
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This volume summarizes current understanding of the pathogenic role of oxidative stress in the onset and progression of diabetes and its complications, and presents results of studies aimed at regulating oxidatively induced complications through the use of antioxidants.
Examines the presence of impaired microcirculation, capillary hypoxia, and ischemia syndrome in diabetic complications!
Designed to stimulate scientific discussion and curiosity about the causes of diabetes, with contributions from nearly 65 clinicians and researchers who cite more than 1300 sources, Antioxidants in Diabetes Management
  • focuses on stringent control of hyperglycemia to prevent or modify onset and progression
  • promotes the development of intervention strategies because of the therapeutic limitations of hypoglycemic therapy
  • emphasizes the potential synergistic effects of an interlinked antioxidant network
  • investigates the controversy surrounding the significance of oxidative stress markers in diabetes
  • highlights oxidative stress and antioxidant treatment in animal models for juvenile and adult onset diabetes
  • explores the hypothesis that ischemic reperfusion is the primary cause of diabetic polyneuropathy
  • links protein kinase C activation to the development of diabetic vascular complications and the effectiveness of vitamin E in preventing these abnormalities
  • spotlights recent clinical trials of therapeutic effects of antioxidants to reduce insulin resistance
  • and much more!
    Illustrating the therapeutic potential of antioxidants for the treatment of diabetes, Antioxidants in Diabetes Management is an unparalleled reference for endocrinologists, nutritionists and dietitians, cell biologists and biochemists, cardiologists, pathologists, and graduate and medical school students in these disciplines.

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    Selected pages


    Oxidative Stress and Antioxidants The Antioxidant Network aLipoic Acid and Diabetes
    Oxidative Stress in Diabetes Why Does Hyperglycemia Induce the Formation of Reactive Oxygen Species?
    Oxidative Stress Markers in Human Disease Application to Diabetes and to Evaluation of the Effects of Antioxidants
    Plasma Lipid Hydroperoxide and Vitamin E Profiles in Patients with Diabetes Mellitus
    Concentrations of Antioxidative Vitamins in Plasma and LowDensity Lipoprotein of Diabetic Patients
    Oxidative Stress in Diabetes
    Antioxidative Defense in Diabetic Peripheral Nerve Effects of DLa Lipoic Acid Aldose Reductase Inhibitor and Sorbitol Dehydrogenase Inhibitor
    Pathways of GlucoseMediated Oxidative Stress in Diabetic Neuropathy
    Clinical Trials of aLipoic Acid indac Diabetic Polyneuropathy and Cardiac Autonomic Neuropathy
    Oxidative Stress NFKB Activation and Late Diabetic Complications
    Role of Oxidative Stress and Antioxidants on Adhesion Molecules and Diabetic Microangiopathy
    Molecular Basis of aTocopherol Action and Its Protective Role Against Diabetic Complications
    Protein Kinase C Activation Development of Diabetic Vascular Complications and Role of Vitamin E in Preventing These Abnormalities
    Oxidative Stress and Pancreatic 𝜷Cell Destruction in Insulin Dependent Diabetes Mellitus
    Interrelationship Between Oxidative Stress and Insulin Resistance
    Oxidative Stress and Antioxidant Treatment Effects on Muscle Glucose Transport in Animal Models of Type 1 and Type 2 Diabetes

    Experimental Diabetic Neuropathy Oxidative Stress and Antioxidant Therapy
    Antioxidants in the Treatment of Diabetic Polyneuropathy Synergy with Essential Fatty Acids
    A Thioctic AcidGammaLinolenic Acid Conjugate Protects Neurotrophic Support in Experimental Diabetic Neuropathy
    Oxidative Stress and Insulin Action A Role for Antioxidants?

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