Apoptosis: from signaling pathways to therapeutic tools

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New York Academy of Sciences, 2003 - Science - 799 pages
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This volume concerns all aspects of apoptosis from signaling pathways to the therapeutic tools that can be derived from an increasing knowledge about the phenomenon of cell death. Discussed in this volume are cell death and development; Mitochondria as regulators of apoptosis, apoptotic signal transduction pathways inhibitors and activation of apoptosis, receptors as mediators of cell death; apoptosis in human disease, including diabetes, blood diseases, and neurodegenerative and cardiovascular disease, transcriptional and post-transcriptional regulation of apoptosis; chromatin structure and apoptosis; the p53 family; and the cell cycle and cell death. Also discussed are caspases and glutathione.

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