Apoptosis and Its Relevance to AutoimmunityThis volume highlights the recent advances in the basic mechanisms of apoptosis and the application of that knowledge to understanding the impact of defective apoptosis or defective clearance of apoptotic cells on the immune function and the expression of |
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Contents
Inherited and Acquired Death Receptor Defects | 18 |
Tumor Necrosis Factor LigandReceptor Superfamily and Arthritis | 37 |
Intrinsic Death Pathways | 55 |
Role of Bim and other Bcl2 Family Members in Autoimmune | 74 |
Mitochondria Cell Death and B Cell Tolerance | 95 |
Role of Complement and Other Innate Immune Mechanisms | 120 |
Opsonins for Apoptotic Cells and Regulators | 143 |
MFGE8Dependent Clearance of Apoptotic Cells | 162 |
Apoptosis and Glomerulonephritis | 188 |
| 205 | |
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Common terms and phrases
ALPS antibodies antigen apop apoptosome arthritis autoantibodies autoimmune disease autoimmune lymphoproliferative syndrome autophagy autoreactive B cells Bcl-2 family members Bcl-2 proteins Bcl-xL BH3-only proteins binding Biol Chem BXD2 c-FLIP calreticulin caspase 9 caspase activation caspase-8 CD8 T cells cell apoptosis cell death cell surface cell survival cellular clearance of apoptotic collectins complement complex cytochrome cytokine death domain death receptor defects deficiency deletion dying cells expression factor FADD Fas ligand FasL function gene glomerular glomerulonephritis human immune response immune system Immunol impaired induced inflammation inflammatory inhibit inhibitor interaction kinase lectin ligand lymphocytes lymphoid macrophages mechanisms mediated membrane mesangial cell mice mitochondrial molecules Natl Acad Sci necrosis necrotic negative selection neutrophils NF-B numbers pathway patients phagocytes phagocytosis phenotype phosphatidylserine pro-apoptotic pro-survival Proc Natl Acad proliferation promote regulation release role scavenger receptors serum signaling SP-A synovial fibroblasts thymocytes tissue transgenic trigger vitro vivo XIAP
Bibliographic information
| Title | Apoptosis and Its Relevance to Autoimmunity Volume 9 of Current directions in autoimmunity |
| Editor | Keith B. Elkon |
| Edition | illustrated |
| Publisher | Karger Medical and Scientific Publishers, 2006 |
| ISBN | 3805580363, 9783805580366 |
| Length | 210 pages |
| Subjects | › › Medical / Immunology Science / Life Sciences / Cell Biology |
| Export Citation | BiBTeX EndNote RefMan |