Aptamers in Bioanalysis
This is the first book to detail bioanalytical technologies and methods that have been developed using aptamers in analytical, medical, environmental, and food science applications. After an introduction to aptamers, aptamer targets, and their general uses, it discusses different applications with particular attention to the comparison between aptamer-based biosensors and methods versus the corresponding immunosensors. Examples of aptamer-based diagnostic techniques include whole-cell protein profiling (proteomics) and medical diagnostics for the distinction of diseased versus healthy states. This is a core reference for analytical chemists, electrochemists, pharmaceutical/medicinal chemists, biotechnologists, and others.
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adenosine affinity amplification Anal Chem 79 analysis analyte antibodies applications aptamer selection aptamer spot aptamer-based aptamer-modified aptazyme assay AuNPs Berezovski binding Biol Biosens Bioelectron biosensor Biotechnol buffer capillary electrophoresis capture carbon nanotube catalytic cells Chem Chem Soc 127 chiral cocaine complementary complex concentration decrease detection limit detection of thrombin developed dissociated DNA aptamer DNAzyme duplex electrode Ellington enantiomer enzyme equilibrium mixture Famulok Figure fluorescence fluorophore formation function G-quadruplex hairpin hemin Hianik hybridization immobilized interactions JAm Chem Soc Klussmann koff Krylov label-free layer ligands lysozyme Mascini molecular nanoparticles NECEEM NECEEM-based neutravidin Non-SELEX Nucleic Acids Res oligonucleotide peak polymerase probe quantum dots recognition redox redox label sample selection of aptamers SELEX sensitive sensor separation sequence serum signaling aptamers solution specific ssDNA strand structure substrate surface plasmon resonance Szostak target molecule temperature thrombin tion Tombelli Toulm´e vitro selection voltammetry Wang Willner