Arterial Chemoreceptors: New Directions and Translational PerspectivesEstelle B. Gauda, Maria Emilia Monteiro, Nanduri Prabhakar, Christopher Wyatt, Harold D. Schultz This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date information concerning the carotid body and oxygen sensing in health and disease. This volume is a required text for all researchers in the field of arterial chemoreception and will provide a valuable reference source for years to come. |
Contents
1 | |
What Is the Point of the Peak? Assessing SteadyState Respiratory Chemoreflex Drive in High Altitude Field Studies | 13 |
Hypoxia Regulates MicroRNA Expression in the Human Carotid Body | 24 |
TASK1 K2P3 and TASK3 K2P9 in Rabbit Carotid Body Glomus Cells | 35 |
Molecular Characterization of Equilibrative Nucleoside Transporters in the Rat Carotid Body and Their Regulation by Chronic Hypoxia | 42 |
Mitochondrial Complex I Dysfunction and Peripheral Chemoreflex Sensitivity in a FASTKDeficient Mice Model | 51 |
Topical Application of Connexin43 Hemichannel Blocker Reduces Carotid BodyMediated Chemoreflex Drive in Rats | 61 |
Proinflammatory Cytokines in the Nucleus of the Solitary Tract of Hypertensive Rats Exposed to Chronic Intermittent Hypoxia | 69 |
Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Preclinical Mouse Model | 109 |
Role of Estradiol Receptor Beta ERβ on Arterial Pressure Respiratory Chemoreflex and Mitochondrial Function in Young and Aged Female Mice | 115 |
Chronic Heart Failure Abolishes Circadian Rhythms in Resting and Chemoreflex Breathing | 129 |
High Fat Feeding in Rats Alters Respiratory Parameters by a Mechanism That Is Unlikely to Be Mediated by Carotid Body Type I Cells | 137 |
Leptin in the Commissural Nucleus Tractus Solitarii Increases the Glucose Responses to Carotid Chemoreceptors Activation by Cyanide | 143 |
Chronic Intermittent Hypoxia in Premature Infants The Link Between Low Fat Stores Adiponectin Receptor Signaling and Lung Injury | 150 |
Myoinositol Effects on the Developing Respiratory Neural Control System | 159 |
Adrenal Medulla Chemo Sensitivity Does Not Compensate the Lack of Hypoxia Driven Carotid Body Chemo Reflex in Guinea Pigs | 167 |
Central Hypoxia Elicits LongTerm Expression of the Lung Motor Pattern in Premetamorphic Lithobates Catesbeianus | 75 |
Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia | 83 |
Adenosine Mediates Hypercapnic Response in the Rat Carotid Body via A2A and A2B Receptors | 89 |
Acute Effects of Systemic Erythropoietin Injections on Carotid Body Chemosensory Activity Following Hypoxic and Hypercapnic Stimulation | 94 |
Carotid Body Dysfunction in DietInduced Insulin Resistance Is Associated with Alterations in Its Morphology | 103 |
A Tribute to Machiko Shirahata MD DMSc 19502016 | 175 |
A Tribute Constancio González Martinez MD PhD 19492015 | 178 |
Concluding Remarks | 181 |
Composite Pictures from Conference | 184 |
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Common terms and phrases
activity acute adenosine Adiponectin AdipoR1 Advances in Experimental altitude animals Appl Physiol Arterial Chemoreceptors Biol blood pressure brain brainstem breathing carotid body carotid body CB carotid sinus carotid sinus nerve central central chemoreceptors channels CHBa chemo chemoreflex Chile chronic CIBER circadian rhythms Conde cysteine cytokines E. B. Gauda effect Experimental Medicine expression FASTK FiO2 function Gauda gene glomus cells glucose Gonzalez hemichannels human hypercapnia hyperoxia hypertension hypopnea hypoxia hypoxic hypoxic response increased intermittent hypoxia ISAC Iturriaga leptin levels light/dark lung Medicine and Biology metabolic microRNA miRNA mitochondrial mRNA myo-inositol neurons normoxia normoxic oxygen oxygen sensing peripheral Prabhakar protein rat carotid body rat CB receptors reflex regulation Respir Physiol Neurobiol response to hypercapnia response to hypoxia role rotenone sleep apnea Springer International Publishing Springer Nature 2018 SS-CD studies tests tion tissue type I cells Universidad Valladolid ventilation