Arterial Chemoreceptors: New Directions and Translational Perspectives

Front Cover
Estelle B. Gauda, Maria Emilia Monteiro, Nanduri Prabhakar, Christopher Wyatt, Harold D. Schultz
Springer, Oct 24, 2018 - Medical - 187 pages
This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date information concerning the carotid body and oxygen sensing in health and disease. This volume is a required text for all researchers in the field of arterial chemoreception and will provide a valuable reference source for years to come.
 

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Contents

O2CO2 Biological Detection to Homeostatic Control
1
What Is the Point of the Peak? Assessing SteadyState Respiratory Chemoreflex Drive in High Altitude Field Studies
13
Hypoxia Regulates MicroRNA Expression in the Human Carotid Body
24
TASK1 K2P3 and TASK3 K2P9 in Rabbit Carotid Body Glomus Cells
35
Molecular Characterization of Equilibrative Nucleoside Transporters in the Rat Carotid Body and Their Regulation by Chronic Hypoxia
42
Mitochondrial Complex I Dysfunction and Peripheral Chemoreflex Sensitivity in a FASTKDeficient Mice Model
51
Topical Application of Connexin43 Hemichannel Blocker Reduces Carotid BodyMediated Chemoreflex Drive in Rats
61
Proinflammatory Cytokines in the Nucleus of the Solitary Tract of Hypertensive Rats Exposed to Chronic Intermittent Hypoxia
69
Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Preclinical Mouse Model
109
Role of Estradiol Receptor Beta ERβ on Arterial Pressure Respiratory Chemoreflex and Mitochondrial Function in Young and Aged Female Mice
115
Chronic Heart Failure Abolishes Circadian Rhythms in Resting and Chemoreflex Breathing
129
High Fat Feeding in Rats Alters Respiratory Parameters by a Mechanism That Is Unlikely to Be Mediated by Carotid Body Type I Cells
137
Leptin in the Commissural Nucleus Tractus Solitarii Increases the Glucose Responses to Carotid Chemoreceptors Activation by Cyanide
143
Chronic Intermittent Hypoxia in Premature Infants The Link Between Low Fat Stores Adiponectin Receptor Signaling and Lung Injury
150
Myoinositol Effects on the Developing Respiratory Neural Control System
159
Adrenal Medulla Chemo Sensitivity Does Not Compensate the Lack of Hypoxia Driven Carotid Body Chemo Reflex in Guinea Pigs
167

Central Hypoxia Elicits LongTerm Expression of the Lung Motor Pattern in Premetamorphic Lithobates Catesbeianus
75
Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia
83
Adenosine Mediates Hypercapnic Response in the Rat Carotid Body via A2A and A2B Receptors
89
Acute Effects of Systemic Erythropoietin Injections on Carotid Body Chemosensory Activity Following Hypoxic and Hypercapnic Stimulation
94
Carotid Body Dysfunction in DietInduced Insulin Resistance Is Associated with Alterations in Its Morphology
103
A Tribute to Machiko Shirahata MD DMSc 19502016
175
A Tribute Constancio González Martinez MD PhD 19492015
178
Concluding Remarks
181
Composite Pictures from Conference
184
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