The replacement or augmentation of failing human organs with artificial devices and systems has been an important element in health care for several decades. Such devices as kidney dialysis to augment failing kidneys, artificial heart valves to replace failing human valves, cardiac pacemakers to reestablish normal cardiac rhythm, and heart assist devices to augment a weakened human heart have assisted millions of patients in the previous 50 years and offers lifesaving technology for tens of thousands of patients each year. Significant advances in these biomedical technologies have continually occurred during this period, saving numerous lives with cutting edge technologies. Each of these artificial organ systems will be described in detail in separate sections of this lecture.
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afterload aorta aortic artery artiﬁcial Artificial Heart Valves ARTIFICIAL ORGANS atrial AV node battery beats/min bileaﬂet valve blockage blood ﬂow cannula capillary tubes CARDIAC ASSIST DEVICES cardiac pacemaker centrifugal blood pump centrifugal pump circulatory system conﬁgured dacron deﬁbrillator depolarization dialysis cartridge dialysis centers dialysis machine dialysis system ECG waveform electrical electrode epoxy top evaluated excitatory fibrillation ﬂexible ﬂow ﬂow ﬁeld ﬂuid glomerulus HEART AND CARDIAC heart rate hemodialysis hemolysis human heart inlet ions kidney left ventricle loop LVAD mass transfer Medtronic membrane meq/L mock circulatory system muscle natural heart nephron node normal sinus rhythm outlet pacemaker lead pacing PACs pathway positive displacement pressure gradient prosthetic heart valves pulsatile purkinje fibers pyrolytic carbon QRS complex reuse right atrium right ventricle SA node seen in Figure shown in Figure sutures technologies tilting disk valve tubule typical dialysis valve leaﬂets valve oriﬁce vasa recta vein velocity ventricular assist device wave
Page 64 - Rosenberg G, Snyder AJ , Landis DL, Geselowitz DB, Donachy JH and Pierce WS: An electric motor driven total artificial heart: Seven months survival in the calf.
Page 1 - Ventricles - The ventricles have thick walls as compared to the thin walls of the atria. They must pump blood out of the heart to the lungs and other distant parts of the body. The heart also contains many important valves. The tricuspid valve is located between the right atrium and the right ventricle. It prevents the backflow of blood into the atrium after the contraction of the right ventricle. The bicuspid valve, or mitral valve, is situated between the left atrium and the left ventricle. It...
Page 1 - The pulmonary valve is located between the right ventricle and the pulmonary artery, a blood vessel that carries blood to the lungs.
Page 57 - Baldwin, JT, Tarbell, JM, Deutsch, S., Geselowitz, DB, "Mean Flow Velocity Patterns Within a Ventricular Assist Device,
Page 57 - Birks EJ, Yacoub MH, Banner NR, Khaghani A. The role of bridge to transplantation: should LVAD patients be transplanted? Curr Opin Cardiol 2004; 19: 148-153.