Aspects of the Cytoskeleton

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Elsevier, Sep 2, 2011 - Science - 384 pages
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This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in this volume remains on the microfilament structure, some discussion has been included in this volume to illustrate the similarities and differences between the three cytoskeletal elements namely the actin microfilament, the intermediate filaments and the microtubules.
 

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Contents

The Cytoskeleton of the Platelet
1
The Actin Cytoskeleton in the Apical Domain of Epithelial Cells
25
The Connection Between Actin ATPase and Polymerization
49
Spectrin Function A Survey of Genetic Systems from Drosophila to Humans
67
Structure and Function of Villin
89
Roles of the Actin Cytoskeleton and Myosins in the Endomembrane System
119
The BRG1 and the Actin Filament System
135
Ionic Waves Propagation Along the Dendritic Cytoskeleton as a Signaling Mechanism
163
Regulation of the Actin Cytoskeleton by Phospholipids
201
Lipid Interactions of Cytoskeletal Proteins
221
Embryo Morphogenesis and the Role of the Actin Cytoskeleton
251
Mechanisms of Ion Transport Regulation by Microfilaments
285
DomainSpecific Phosphorylation as a Regulator of Intermediate Filaments
307
Abbreviations and Acronyms
333
Index
335
Copyright

The Functional Role of Actin Cytoskeleton Dynamics and Signaling
181

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