Atherosclerosis: Gene Expression, Cell Interactions, and Oxidation

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R. T. Dean, David T. Kelly
Oxford University Press, 2000 - Medical - 450 pages
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Provides a critical review of the oxidative theory of atherosclerosis as well as highlighting new trends in research from basic to clinical, academic to commercial. The contributions of diabetes, vascular dysfunction, blood coagulation, plaque rupture, oxidative stress, lymphocytes, macrophages, growth factors, cytokines, and oxysterols to atherogenesis are all discussed, as are the roles of smooth muscle and endothelial cells. As well as a summary of the methods of diagnosis, the future prospect of using biochemical markers from plasma is also discussed. There is a critical look at gene therapy and other future therapeutic strategies based on the molecular and cellular causes of atherosclerosis. Each chapter is written by two or more authors from different laboratories to ensure a balanced approach. It should be of use to all biomedical researchers with a specialist or passing interest in atherosclerosis research. This book is intended for biomedical researchers with a specialist or passing interest in atherosclerosis research.

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Contents

Shanlin Fu Cell Biology Group The Heart Research Institute Camperdown
1
Diabetes and atherosclerosis
24
Antioxidant intervention studies in animals
46
Copyright

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About the author (2000)

Roger Dean is at The Heart Research Institute, Sydney. David Kelly is at The Heart Research Institute, Sydney.

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