An Atlas of Preimplantation Genetic Diagnosis: An Illustrated Textbook & Reference for Clinicians, Second Edition

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CRC Press, Dec 22, 2004 - Medical - 302 pages
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Extensively illustrated, this atlas is a manual for the establishment and realization of PGD within the framework of assisted reproduction and genetics services. Fully revised and updated, the atlas includes descriptions of the authors' pioneering work on polar body based PGD for genetic and chromosomal disorders. The authors' novel experience of PGD for late-onset disorders with genetic predisposition will be of special interest. Their accumulated PGD experience for poor-prognosis IVF patients presents further evidence of the improvement of clinical outcome and the requirement for meiotic error testing for a higher accuracy of preselecting aneuploidy-free embryos for transfer.
 

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Contents

Normal and abnormal human preimplantation development in relation to preimplantation
7
Micromanipulation and biopsy of polar bodies and blastomeres
15
Nuclear transfer techniques for preimplantation diagnosis and prospect for artificial
23
Preimplantation diagnosis for aneuploidies
29
Preimplantation diagnosis for translocations
43
Preimplantation diagnosis for singlegene disorders
49
Future perspectives for preimplantation diagnosis
63
Normal and abnormal human preimplantation development in relation to preimplantation
73
Micromanipulation and biopsy of polar bodies and blastomeres
103
Preimplantation diagnosis for aneuploidies
141
Preimplantation diagnosis for translocations
179
Preimplantation diagnosis for singlegene disorders
213
lndex
281
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