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75 Figure 80 Figure abnormalities acid maltase deficiency adult ATP-ase pH 9 ATP-ase reaction atrophic fibres axon Becker dystrophy biopsy shows carnitine Central core disease central nuclei childhood chronic SMA congenital fibre type congenital myopathy connective tissue cytoplasm Deltoid biopsy dermatomyositis diagnosis disorders distal Duchenne dystrophy Electron microscopy facioscapulohumeral fascicles fibre atrophy fibre type disproportion fibres Figures fibrosis glycogen histochemical histology hypertrophied fibres hypotonia innervation lesion Limb girdle syndrome lipid lysosomes malignant hyperthermia membrane metabolic mild mitochondria morphological motor neuron disease motor units muscle biopsy muscle cell muscle fibres muscular dystrophy myasthenia gravis myofibrils myosin myositis myotonia myotonic dystrophy NADH-TR necrotic fibres Nemaline myopathy nerve Neurol Sci Neurology normal onset oxidative enzyme reaction pathological patients polymyositis proximal muscle weakness re-innervation reveals Serial section shown in Figures skeletal muscle small fibres Small group atrophy spinal muscular atrophy staining steroid type 1 fibres type grouping usually vacuoles variation in fibre