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IN VITRO AND IN VIVO
Hematopoiesis in short term culture
Clinical application of in vitro hematopoiesis
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abnormal Acad acid activity acute leukemia antigen appear associated basophils biochemical Biol blast blood cells bone marrow Brit cellular characterized chromatin chromosome chronic myelogenous leukemia Clin clinical clonal clone colony stimulating Courtesy of Dr culture cytochemical cytoplasm deficiency degranulation differentiation disease disorders dyserythropoietic electron microscopy enzyme eosinophil erythroblasts erythrocytes erythroid erythroid cells erythropoiesis esterase function gene GM-CSF granulocytes Haematol Hematology hematopoietic hemoglobin hemolytic anemia hereditary human identified Immunol leukemic leukocytes lineage lymphocytes lymphoid macrophages markers mast cells megakaryocyte megaloblastic membrane metabolic mitochondria molecular monoclonal antibodies monocytes mononuclear morphological myeloblast myelocyte myelogenous leukemia myeloid Natl neutrophils normal normoblasts nuclear nucleus particles patients peripheral blood peroxidase phagocytic phagocytosis phenotype phosphatase platelets pluripotent precursors Proc progenitor cells proliferation promyelocyte protein reaction receptor red cells Reproduced from ref reticulocyte seen smears specific spleen stained stem cell studies syndrome synthesis thalassemia tissue ultrastructural vacuoles vitro Zucker-Franklin