Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity
In the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.
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2 Follicle Stages and Follicular Atresia
3 Follicular Atresia as a Proliferative and Inflammatory Event
4 The Cortex and Cellular Stromatolysis
5 The Ovulatory Period as Acute Inflammatory Response to Oxidative Stress and Follicle Cell Harvest
6 Corpus Luteum Life Cycle with Focus on Capillary Sprouting and Regression Eosinophils and KITPositive Cells
7 Intraovarian Oocyte Release IOR with Severe Tissue Damage
8 Vascular Stromatolysis and Vascular Luteolysis for Bulk Tissue Removal
9 Polycystic and Postmenopausal Ovaries with Negligible Mast Cells
10 CytokeratinPositive Cells as DendriticLike Cells and Potential Albumin Coexpression in Follicles and CL
11 Aspects of Immunological Control Novel Concepts Challenges and Clinical Perspectives
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Adapted from Spanel-Borowski albumin albumin-positive cells Anat antral follicles antrum apoptosis apoptotic arrow asterisk autophagy basement membrane beagle Biol Borowski bovine CL bovine corpus luteum bovine ovary capillary sprouts cell death cell type CK expression CK-positive cells CK-positive granulosa cells corpus luteum cortex cortical stroma cyclic cytoplasmic shedding dendritic cells endothelial cells eosinophils follicle cells follicles Fig follicular atresia FVIIIr golden hamsters granulosa cell layer Granulosa cell subtypes granulosa cells growth factor Hum Reprod immature Immunol immunostaining inflammatory INIM function innate immunity interstitial cortical interstitial gland cells leukocytes lipoprotein luteal cells lutein luteolysis Mammalian Ovary mast cells melatonin microvascular bed microvessel nerve fibers oocyte oocyte release ovarian cycle ovary ovulation ovulatory oxidative stress oxLDL PMSG application polycystic preantral follicles preovulatory follicle rats receptor regression Reibiger reproductive Ricken signaling Spanel staining steroidogenic stroma structural luteolysis superovulated thecal cell thecal cell layer tumor vascular luteolysis Vilser whole-body X-irradiation zona pellucida