Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity

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Springer Science & Business Media, Oct 12, 2012 - Medical - 141 pages
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In the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.
 

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Contents

1 Introduction
1
2 Follicle Stages and Follicular Atresia
9
3 Follicular Atresia as a Proliferative and Inflammatory Event
23
4 The Cortex and Cellular Stromatolysis
31
5 The Ovulatory Period as Acute Inflammatory Response to Oxidative Stress and Follicle Cell Harvest
38
6 Corpus Luteum Life Cycle with Focus on Capillary Sprouting and Regression Eosinophils and KITPositive Cells
61
7 Intraovarian Oocyte Release IOR with Severe Tissue Damage
80
8 Vascular Stromatolysis and Vascular Luteolysis for Bulk Tissue Removal
99
9 Polycystic and Postmenopausal Ovaries with Negligible Mast Cells
108
10 CytokeratinPositive Cells as DendriticLike Cells and Potential Albumin Coexpression in Follicles and CL
115
11 Aspects of Immunological Control Novel Concepts Challenges and Clinical Perspectives
127
Index
133
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About the author (2012)

Katharina Spanel-Borowski studied human medicine at Bonn from 1963 to 1969. She subsequently specialized in Pathology and Anatomy at Ulm, Lübeck, and Basel, in Germany and Switzerland, before serving as head of the Institute of Anatomy at the University of Leipzig from 1997 to 2009. She has published on the functional morphology of the ovary since 1980 and has promoted the concept of innate immunity control in the ovary on the basis of retrospective analysis performed during early retirement.

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