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Autoimmunity and toxicology Immune disregulation induced by drugs
Drug and chemicalinduced autoimmune diseases in humans
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acetylator acetylator phenotype acid activation adjuvant adverse reactions Allergy animals antigens antinuclear antibodies Arthritis Rheum assay associated autoantibodies autoantigens autoimmune disease binding chemical Clin clinical complement compounds covalent cytokines cytotoxic D-penicillamine develop diphenylhydantoin dose drug drug-induced effects epitopes erythrocytes expression factors function gene genetic Gleichmann glomerulonephritis halothane halothane hepatitis helper T cells hepatitis HgCl2 histones human hydralazine hydralazine-induced lupus hypersensitivity immune complex immune response immune system immunogenic immunoglobulin Immunol immunological increased induced inhibition injection interaction isoniazid liver lymph node lymphocytes lymphoid macrophages mechanisms membrane metabolism metabolites MHCII mice molecules mouse murine nitrofurantoin normal observed pathogenesis Pharmacol plasma procainamide procainamide-induced lupus production protein rapid acetylators rats reactive receptor rheumatoid arthritis role serum slow acetylators specific stimulation studies suppressor suppressor cells surface symptoms syndrome systemic lupus erythematosus therapy thyroglobulin thyroid tibodies tion tissue toxic treatment vitro zimeldine