Autosomal dominant polycystic kidney disease

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Karger, 1995 - Medical - 192 pages
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Recent years have witnessed an explosion of knowledge on autosomal dominant polycystic kidney disease (ADPKD), one of the most common of all genetic diseases. The major ADPKD gene, PKD1, has now been identified and progress is being made towards identifying the PKD2 gene.
With contributions by leading researchers in the field, this volume stems from a seminar held in Vimercate, Italy, designed to discuss and evaluate the latest advances. The contributions update knowledge regarding various aspects of ADPKD, including molecular genetics, renal cystogenetic mechanisms and clinical considerations. They also present interesting epidemiological data and discuss ethical problems and issues relating to genetic counselling. In addition, an extensive section containing poster presentations provides the reader with an excellent overview of current directions in research on ADPKD.

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Pathogenesis of Renal Cysts in Dominantly Inherited Polycystic Kidney Disease
The Patient with ADPKD on Maintenance Hemodialysis
New Insights and Unanswered

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